The Museu Nacional Frei Manuel do Cenáculo is located in the historic center of Évora in the Former Palace of the Archbishop of Évora. It preserves notable collections of Painting, Sculpture, Archeology, Jewelery, Furniture, Nature, and Decorative Arts.

Of note is the large Flemish altarpiece depicting the Life of the Virgin, from the old chancel of the Cathedral of Évora.